When the body’s automatic functions stop working

Intranasal mechanical stimulation, or INMEST, is a treatment method that stimulates the brain to balance the autonomic nervous system. The method alleviates symptoms caused by autonomic dysfunction. It was developed by researchers partially affiliated with Karolinska Institutet in Stockholm, Sweden.

This is INMEST

Pulse, blood pressure, and breathing – your autonomic nervous system controls what you don’t consciously control. But hundreds of thousands of individuals, just in Sweden, suffer from the malfunction of these automatic functions – a condition known as autonomic dysfunction. For them, INMEST offers a new hope!

INMEST – How it works

Unlike many other treatments, INMEST does not require surgery and is not a medication. Instead, it is a medical device that allows individuals to manage their own treatment at home.

All that’s needed is a handheld device. Through nerves in the nose, it influences the areas of the brain that control the autonomic nervous system.

The research on this method is still in its early stages, but the results so far are promising. With your help, we can take the research to the next level!

The opposite of stress – also beneficial for the body’s immune system

Our experience is that repeated INMEST counteracts hypertension, elevated heart rate, and promotes calmer breathing – the opposite of what stress causes. We also know that with repeated INMEST, other, more profound effects are observed.

Among other things, the body’s immune system is influenced. Regulatory T-cells, sometimes called the “guardians” of the immune system, respond to the treatment, indicating anti-inflammatory effects.

These effects can also be linked to “anti-stress,” as it is well known that prolonged stress can lead to inflammation. However, much more research remains to be done.

Current updates

  • Clinical study on Sjögren’s disease

    Sjögren’s disease is an autoimmune systemic condition that primarily affects the body’s exocrine glands, such as the salivary and tear glands. These glands become inflamed and function poorly, leading mainly to dry mouth and dry…

    Läs mer…

  • We are looking for a research leader for a study on atopic dermatitis

    There is a large group of patients with atopic dermatitis who do not receive satisfactory relief from their treatment, yet do not qualify for biologic drugs. We want to study this group, and if our…

    Läs mer…

”A method with endless possibilities!”

The idea behind INMEST is so simple – yet it could lead to a revolution 

Autonomic dysfunction has many causes and affects hundreds of thousands in Sweden alone. If ongoing research into INMEST confirms what we have already observed, there may be almost no limit to how many people could benefit from it.

Since its founding in 2017, the foundation has contributed funding and conducted several research studies, including INMEST as a treatment for chronic fatigue syndrome (ME), chronic obstructive pulmonary disease (COPD), and dry eye disease (DED).

But what exactly happens in the body with INMEST? Read on, and we will try to explain.

…and below, Jan-Erik Juto explains how it all began.

A foundation for research

How it all began  

Vagus nerve stimulation has been used for over 100 years, but never through the nose – until now. Jan-Erik discovered that the nervous system affects inflammation and developed a simple, yet promising treatment.

“”It seemed that the nasal mucous membranes could respond to levels of moisture and mold that were far below the thresholds that were considered relevant at the time. But there was no good way to objectively measure the swelling.”

What started with an aquarium pump has today become a method being explored for nasal congestion, migraines, and autoimmune diseases.

Read more about how INMEST came to be.

Why a foundation for Inmest?

The Inmest Foundation was established to improve people’s lives. Today, there are many treatment methods for conditions associated with autonomic dysfunction, but they are often complicated or come with troublesome side effects. INMEST is a treatment for autonomic dysfunction that has no known side effects and can be performed by the patient at home.

We are convinced that this method can offer a chance for a better life for many patients, both in Sweden and around the world. That is why we want to spread awareness about Inmest.

Scientific studies are needed for the method to gain traction. We conduct studies ourselves and fund studies conducted by others. However, research is expensive. Therefore, one of our most important tasks is to raise funds for the research.

Read more about the foundation’s work and how medical studies are conducted.

Would you like to contribute to the research?